Hair Of The Dog?

Filed in Science and Health by on May 10, 2010

Whenever I’ve had a little too much “fun” (and ended up paying for it) my brother would always say, “hair of the dog.”  Looks like he had a point.

Scientists have discovered the molecule in the brain that leads to hangovers. The neuropeptide, a brain-signalling molecule, is believed to cause the body to experience withdrawal symptoms as the brain tries to adapt to different intoxication levels.

The neuroscientists from the University of Southampton’s School of Biological Sciences studied the simple brains of C. elegans worms, which have a makeup similar enough to the human brain when intoxicated or dependent on alcohol.

What they found was striking.

[…]

“This research showed the worms displaying effects of the withdrawal of alcohol and enables us to define how alcohol affects signalling in nerve circuits which leads to changes in behavior,” said professor Lindy Holden-Dye, a neuroscientist of the University’s School of Biological Sciences and member of Southampton Neurosciences Group (SoNG), who led the study.

When the worms were given small doses of alcohol during their withdrawal their irritable behaviors eased. Unfortunately, this approach to combating a hangover also increases the chances for alcohol dependency.

Science rocks…  And is important:

“This is leading to new ideas for the treatment of alcoholism,” Holden-Dye said. “Our study provides a very effective experimental system to tackle this problem.”

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A stay-at-home mom with an obsession for National politics.

Comments (6)

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  1. RSmitty says:

    When the worms were given small doses of alcohol during their withdrawal their irritable behaviors eased. Unfortunately, this approach to combating a hangover also increases the chances for alcohol dependency.

    😯
    A college-friend of mine, now totally sober, always insisted his habit of “chasing” his hangovers (with more beer) was his cure. Yeah, he later realized he was an alcoholic and addressed it, but I used to tell him he just loved drinking too much and that was his excuse. Well, freak, I guess he was right.

  2. anon says:

    So that’s what that worm was doing in my bottle of tequila.

  3. Scott P says:

    I have a question: How exactly does one know when a worm is acting irritable? Follow-up question: How does one go about getting a job where one gets paid to get worms drunk? Cause this sounds more like the work of a sociopathic middle schooler. Science does indeed rock!

  4. anon says:

    I know what I’m bringing to the next Drinking Liberally.

  5. nemski says:

    Unfortunately, this approach to combating a hangover also increases the chances for alcohol dependency.

    Could be an issue.

  6. I’m curious to see the behavior of a drunk worm? Does it try to mate with itself?